Recombinant human VAV2   

Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN

濃度：1mg/ ml

來(lái)源：Recombinant Human

純度：≥95% SDS-PAGE

表達(dá)系統(tǒng)：Escherichia coli

標(biāo)簽：His tag

蛋白長(zhǎng)度：Full length protein

內(nèi)毒素水平：<1.000 Eu/µg

純化方法：HPLC

應(yīng)用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質(zhì)期：1年

VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.

產(chǎn)品名稱：Rabbit Anti-VAV2  antibody

Rabbit Anti-VAV2  

別名：Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN.          

來(lái)源：Rabbit

克隆類(lèi)型：Polyclonal

濃度：1mg/ml

亞型：IgG

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng)：(predicted: Human,Mouse,Rat,Pig,Cow,Dog)

理論分子量：97kDa

免疫原：KLH conjugated synthetic peptide derived from human VAV2

保存：-20℃
保質(zhì)期：1年

單克隆抗體

產(chǎn)品名稱：Anti-VAV2 antibody

Mouse Anti-VAV2 

別名：Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN.  

來(lái)源：Mouse

克隆類(lèi)型：Monoclonal

濃度：1mg/ml

亞型：IgG

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng): Human

理論分子量：97kDa

免疫原：KLH conjugated synthetic peptide derived from human VAV2

保存：-20℃
保質(zhì)期：1年

VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.